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Heart Inflammation Risk for Young Men Higher After Vaccination Than After COVID-19: Study

The risk of heart inflammation is higher for men as old as 39 after Moderna COVID-19 vaccination than after COVID-19 infection, according to a new study.

Researchers in England analyzed hospital admissions with myocarditis, a form of health inflammation, among the vaccinated between Dec. 1, 2020, and Dec. 15, 2021.

They estimated that the second dose of Moderna’s vaccine, which is advised for a two-dose primary series, leads to 97 myocarditis cases per million above baseline in the first 28 days after vaccination for men younger than 40. That’s up from 16 additional cases per million of myocarditis after a positive COVID-19 test and before vaccination.

Researchers also estimated that a first dose of Pfizer’s vaccine led to four additional myocarditis events per million, and that a first dose of Moderna’s vaccine led to 14 additional myocarditis cases per million, in the males younger than 40. A second dose of Pfizer’s vaccine was associated with 14 additional myocarditis events per million in the age group.

Both the Moderna and Pfizer vaccines have long been associated with heart inflammation, but Moderna’s has been linked with much higher rates.

Moderna and Pfizer did not respond to ...